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butalbital will lessen the level or influence of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.cenobamate will enhance the level or result of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Observe Intently. Look at a dose reduction of CYP2C19 substrates, as clinically ideal, when mad